A personal genome (dna),story

A personal genome (dna) story

A few years back I had my genome done by http://www.23andme.com. I am curious about most things and look for supporting empirical evidence just because, so it was a no brainer for me. 

The quantity and quality of the data that came back was both revealing and impressive to be sure. Ancestry, which is of course fun, as well as traits, health risks and drug responses feature as categories for the data. 

What really caught my attention initially was inherited conditions. Of the 50+ bad ones currently tracked by 23andme, no markers in my dna, however I am a carrier for hemochromatosis, an blood iron condition. 

Boom, daughters getting their dna done, mom and a few others as well. Relief, both daughters are condition free but carriers as well. 

I have been having fun with my dna for a good while, an example, I have: 

  • 3.0% Neanderthal in my dna; 
  • 12.6% chance of getting Alzheimer’s; 
  • a marker giving higher than average odds of living to a hundred or more; 

So, half wild and crazy, I am going to be around here for a while!

Recently, our (the girl from Ipanema and myself) oldest daughter developed multiple breast lumps and other conditions simultaneously. 

Dads do what dads do. While on the plane scouring dear daughter’s dna, her mother’s dna and my mother’s dna on the iPad for information for the the doctors, a feeling of confidence came over me. The doctors concurred, the tests became more specific and dear daughter has an encouraging prognosis. 

Words do not do justice to watching the radiant faces of one’s daughter and partner emerging from breast cancer test results. Gratitude to 23andme, doctors, daughter and partner! 

A little caveat here. The type of dna testing done at 23andme is entry level at an entry level price of around $200. Further more detailed and complete genetic testing, if required, would be closer to $1000 per. As with anything digital such as dna, the price performance decreases exponentiallyMas per Moore’s Law. It will get cheaper soon. By 2025: $10 all in. 

A parting thought: 

Maternal Line = U4a1, Paternal Line = R1b1b2a1a2f* 

Which means: 

…..out of africa…..a long sojourn in western europe…..a couple of decades in north america…..almost 4 decades exploring the world………..space next….

Yes, the tinker (gypsy) gene is in my dna. 

So anyway, a personal dna story seasoned old roughneck                                                            ‘ddps1.31.05.02015 

The question of everything

2025: disrupt 2 thrive

The question of everything

A contemplation on the need to write new rules to be able to change the world for the better led to a contemplation on writing new math and whether there really is a difference between writing new rules and new math.

Writing new math to solve astrophysics conundrums is commonplace to the likes of Dr. Lawrence Krauss, Dr. Neil Tyson, Dr. Radek Zalenka and Dr. Rodney Mackay.

New math then:

1     big hairy assed grand challenge for humanity

+ 1     exponential technology toolbox

+ 1     percent of GDP

= 3     = phase 1: empowered crowd in 2025 ready for phase 2 to 2050 and beyond

+ 1      percent of GDP

= 4     = phase 2: done deal, pretty much everything is happening

…4                   2

…42

.:.        42 = everything

Col Shepherd and The…

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The question of everything

The question of everything

A contemplation on the need to write new rules to be able to change the world for the better led to a contemplation on writing new math and whether there really is a difference between writing new rules and new math.

Writing new math to solve astrophysics conundrums is commonplace to the likes of Dr. Lawrence Krauss, Dr. Neil Tyson, Dr. Radek Zalenka and Dr. Rodney Mackay.

New math then:

1     big hairy assed grand challenge for humanity

+ 1     exponential technology toolbox

+ 1     percent of GDP

= 3     = phase 1: empowered crowd in 2025 ready for phase 2 to 2050 and beyond

+ 1      percent of GDP

= 4     = phase 2: done deal, pretty much everything is happening

…4                   2

…42

.:.        42 = everything

Col Shepherd and The Stargate Atlantis team were right all along:

 The answer to the question of everything really is 42.

 

So anyway, a bit of new roughneck math

‘ddj1.30.05.02015